New Bioprocessing Concepts

The industry is driving towards intensified manufacturing solutions to provide a more efficient, sustainable and smaller footprint which provides a lower-cost solution. These multi-configurable approaches require flexible, plug-and-play solutions that enable the ability to support multiple modalities such as biologics, vaccines and gene therapy.

We are creating new bioprocessing concepts to support intensified and integrated approaches with continuous purification that will provide robust and reliable manufacturing aided by advanced control strategies. Examples include the creation of a high cell density seed train concept with closed aseptic seed train to production requiring fewer unit operations than traditionally used. Efforts to further improve cell lines with higher titer and reduced impurities will be combined with more efficient downstream technologies that will ultimately lead to further footprint reductions. Sustainable design concepts will be incorporated to further reduce the carbon footprint and waste production.