Maximize MSC Research with Deeper Insights, Automation, and Enhanced Characterization
Mesenchymal stem cells (MSCs) are adult stem cells isolated from various sources such as bone marrow, adipose tissue and umbilical cord. They are multipotent cells with the capacity to differentiate into cell types such as osteocytes (bone cells), chondrocytes (cartilage cells), myocytes (muscle cells) and fat cells of adipose tissue (adipocytes).
MSCs secrete a host of chemical messengers, including chemokines, cytokines, growth factors, metabolic products and small molecules such as microRNAs (miRNAs), which act on neighboring cells to produce biological effects.
The potential of MSCs to differentiate into various cell types and their immunomodulatory functions make them attractive candidates for regenerative therapies and chronic inflammatory disease treatment.
Effective advanced cytotherapies require reliable equipment and bioprocesses to move from research to clinical phases and eventually gain regulatory approval. Challenges can include:
- Controlling variability to ensure reproducibility of experiments
- Automating assays to understand and characterize MSCs and their therapeutic effects
- Running assays at throughput to accelerate the development of insights
- Characterizing the phenotype and function of MSCs and affected tissues to measure therapeutic effect of MSCs
- Gaining insight into MSC therapeutic potential through extensive characterization to establish critical quality attributes (CQAs)
MSC Therapy Research & Development Benefits
Gain biological insights into MSC phenotypes and therapeutic effects through in-depth cell characterization
Ensure study reproducibility by effectively managing MSC donor, culture and reagent variability
Ensure patient safety with rapid detection of mycoplasma as well as bacteria and fungi in just three hours
Featured MSC Therapy Research & Development Products
CellCelector Automated Cell Selection and Retrieval Platform
Fully automated solution for the identification, targeted isolation and passaging of the desired stem cell colonies or clones.
Automated counting and picking of individual stem cell colonies to access myeloid vs. erythroid colonies, differentiation state, gene expression profiles or gene mutations.
Incucyte® Live-Cell Analysis Platform
Enables real-time, live-cell analysis directly inside your incubator and deeper, physiologically relevant information about your cells. Never miss powerful insights again with the Incucyte® Live-Cell Analysis System, software, reagents and consumables.
- Study complex immune cell interactions, synaptic activity in neuronal co-cultures, apoptosis, proliferation and much more -with a single platform.
- Enjoy walk-away convenience as images are automatically acquired and analyzed in microplate format, up to six in parallel.
iQue® 3 High-Throughput Cytometry Platform
The iQue® 3 HTS Platform is an integrated instrument, software and reagent system that enables rapid, high-content, multiplexed analysis of cells and beads in suspension.
MSC phenotypic and functional analysis
Immunomodulation and cytokine profiling assessment
Microsart® ATMP Mycoplasma — Rapid Real-time PCR Mycoplasma Detection Kit
Microsart® Mycoplasma qPCR detection kits: a rapid and guideline-compliant solution for mycoplasma detection. These kits are fast, highly specific, sensitive, and compliant with international guidelines.
Microsart® ATMP Sterile Release Detection Kit
Rapid Bacteria and Fungi Detection in Only 3 Hours with Microsart® ATMP Sterile Release Kit. The qPCR-based kit detects a broad range of gram-positive and gram-negative bacterial and fungal contaminants.
Mesenchymal Stem Cell Media
MSC NutriStem® XF supports the isolation and expansion of hMSCs, providing high-quality cultures for research and cell-based therapies.
• Xeno-free, serum-free
• Superior proliferation rate
• Maintain cell characteristics and differentiation potential
• Custom scale-up and optimization services
• Smooth transition from RnD to manufacturing
• Scientific and regulatory support
• cGMP manufactured
• DMF available
