Sartorius MSC Optimization and Characterization Solution

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Sartorius MSC Optimization and Characterization Solution

An automated, high-throughput expansion and characterization solution that accelerates process optimization through CPP and CQA correlation resulting in a robust, scalable, well characterized MSC production process.

  • Process control: Determine optimal expansion in controlled MSC cultures (pH, DO, temperature, stirring speed) with consistent, serum-free, xeno-free MSC medium and 3-hour sterility checkpoints in 100 – 250 mL cultures
  • Automation: Minimize manual work with a multi-parallel bioreactor and walkaway automation advanced flow cytometry and continuous live-cell analysis platforms
  • At-scale throughput: Optimize your MSC production process in 1 - 8 mini bioreactors operated in parallel and perform cell characterization assays in 96- and 384-well plates
  • Extensive characterization: Monitor MSC morphology and growth using live-cell analysis and acquire paracrine effect understanding using advanced flow cytometry analysis
  • Process insight: Gain rapid understanding of the optimal MSC expansion protocol using advanced modeling software and quality characterization analytics to correlate CPPs and CQAs
Contact an MSC Therapy Consultant

Ambr® 250 Modular

Expandable automated benchtop bioreactor system with 2-8 single-use 100-250 mL vessels for accelerated, high-throughput MSC process optimization

MODDE®

Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters

MSC NutriStem® XF Basal Medium

Defined, serum-free, xeno-free MSC expansion medium to maintain normal morphology, stable karyotype, and trilineage differentiation potential

SoloHill® Microcarriers

Sterile, ready-to-use microcarriers in a variety of formats that support rapid and efficient attachment and growth of MSCs in suspension culture

MSCgo™ Differentiation Media

Serum-free, xeno-free MSC trilineage differentiation potential testing (osteogenic, adipogenic, and chondrogenic)

NutriFreez® D10 Cryopreservation Media

Fully defined, serum-free cryopreservation medium for a consistent, high-performance protective environment for MSCs during the freezing, storage, and thawing

Microsart® ATMP

3-hr PCR-based kit for the detection of mycoplasma, bacteria, and fungi for in-process testing of MSC therapeutics

Ambr® 250 Modular

Expandable automated benchtop bioreactor system with 2-8 single-use 100-250 mL vessels for accelerated, high-throughput MSC process optimization

iQue® 3

Advanced high-throughput flow cytometry platform for MSC phenotypic analysis and immunomodulation and cytokine profiling assessment

Incucyte® SX5

Automated, real-time, live-cell analysis platform for quantitative insights into MSC health, morphology, proliferation and function

MODDE®

Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters

iQue® 3

Advanced high-throughput flow cytometry platform for MSC phenotypic analysis and immunomodulation and cytokine profiling assessment

Incucyte® SX5

Automated, real-time, live-cell analysis platform for quantitative insights into MSC health, morphology, proliferation and function

Ambr® 250 Modular

Expandable automated benchtop bioreactor system with 2-8 single-use 100-250 mL vessels for accelerated, high-throughput MSC process optimization

MODDE®

Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters

Incucyte® SX5

Automated, real-time, live-cell analysis platform for quantitative insights into MSC health, morphology, proliferation and function

iQue® 3

Advanced high-throughput flow cytometry platform for MSC phenotypic analysis and immunomodulation and cytokine profiling assessment

Process Insight

Powerful multivariate data analysis tool with interactive visualizations, an intuitive interface, and automatable workflows for comprehensive process understanding

Sartorius MSC Optimization and Characterization Solution Data Sheet Collection

PDF | 17.0 MB

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