Sartorius PSC Exploration and Characterization Solution
A miniaturized, high-throughput, semi-automated solution to enable 2D-to-3D culture transition, optimize CPPs for workflow development, with insight-delivering analytics to establish and track CQAs for process development optimization of iPSCs and derivatives
- Process control: Control pH, DO, temperature, and stirring speed as you explore the expansion and differentiation process of iPSCs and their derivatives in 15 mL cultures. Complete with consistent, serum-free, xeno-free iPSC medium and 3-hour sterility checkpoints for complete control of the process
- Automation: Reduce setup, execution, and handling times with automated iPSC expansion and differentiation as well as walkaway automation characterization
- At-scale throughput: Set up comprehensive DoE approaches with minimal numbers of cells in a 24-48 sample miniaturized assay platform and characterize cells in suspension and adherent cells in 96- and 384-well plates
- Extensive characterization: Acquire differentiation marker information using advanced flow cytometry and detect morphological changes during differentiation using continuous live-cell analysis
- Process insight: Develop process knowledge through process, phenotypic and functional characterization insights
Process Control
MODDE®
Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters
Automation
MODDE®
Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters
At-Scale Throughput
MODDE®
Design of experiment software to enable a seamless transition from planar to suspension culture while identifying critical process parameters
Extensive Characterization
Process Insight
SIMCA®
Powerful multivariate data analysis tool with interactive visualizations, an intuitive interface, and automatable workflows for comprehensive process understanding