Sartorius T-Cell Pilot Solution
Scaled-up, semi-automated expansion and characterization solution to develop process insight through CPP and CQA correlation for a robust CAR-T manufacturing protocol
Process control: Determine optimal growth performance and identify critical process parameters with consistent, serum-free, xeno-free T-cell medium and rapid sterility testing in volumes from 100mL to 250mL
Automation: Rapid process development and process optimization with minimal manual handling and online automated monitoring as well as functional and phenotypic characterization of CAR-T cells
At-scale throughput: Optimize at throughput with 1-8 bioreactors operated in parallel and perform multiplex analysis in 96- and 384-well plates
Extensive characterization: Test CAR-T phenotype and function with multiplex analysis of cells in suspension and profiling in T-cell killing and T-cell health assays
Process insight: Gain rapid understanding of the optimal expansion protocol by analyzing process parameters and characterization data to correlate CPPs and CQAs
Process Insight
Powerful multivariate data analysis tool with interactive visualizations, an intuitive interface, and automatable workflows