- Lab Products & ServicesLab Products & Services
- Bioprocess SolutionsBioprocess Solutions
- CompanyCompany
- ContactContactHeadquarters
Sartorius AG
Weender Landstr. 94-108
37075 Goettingen, GermanyPhone: +49.551.308.0
Fax: +49.551.308.3289
Sartobind STIC® PA 5" 92STPA42D9-FF--A
- Binding of contaminants at high salt concentration
- Simple handling
- High speed polishing
- Less buffer consumption
- Disposable and ready-to-use
Description
Sartobind STIC® membranes are a new group of Salt Tolerant Interaction Chromatography membrane adsorbers. With the primary amine ligand they bind negatively charged impurities such as DNA, host cell proteins, endotoxins and viruses at much higher salt concentrations than known from conventional Q matrices. Sartobind STIC® membranes eliminate the need for feedstream dilution before flowthrough polishing of recombinant proteins and Mabs. The single use product reduces validation cost, consumption of buffers, footprint and speeds up time to bring products to market. The Sartobind STIC family scales linearly within the proven Sartobind SingleSep® formats of Sartobind nano 1 ml (36 cm²) up to larger capsules.
Product properties
| Bed volume |
70 mL
|
| Membrane area |
0,25 m²
|
| Pack size |
4
|
| Connectors |
Sanitary 1/2 - 3/4"
|
| Application |
Polishing
|
| Membrane |
Salt tolerant anion exchanger
|
| Bed height |
4 mm
|
Technical attributes
| Reusable |
No
|
| Pore size |
3 - 5 µm
|
| Bed height |
4 mm
|
| Recommended flow rate |
Membrane volumes
|
| Maximum Venting Pressure |
0.5 bar, 0.05 MPa, 7 psi
|
| Material |
Polypropylene, polyester
|
| Housing material |
Polypropylene (PP)
|
| Chemical compatibility |
Stable in common chromatography buffers, unstable to peroxide and other oxidizing or reactive reagents
|
| Thermal stability |
Sartobind capsules with ion exchange membranes can be autoclaved at 121 °C for 30 min. We recommend one autoclaving cycle only.
|
| Biosafety |
All materials of this product meet the requirements of the current United States Pharmacopoeia (USP) Biological Reactivity tests for Plastic Class VI (Systemic Injection, Intracutaneous and Implantation tests).
|
| Membrane material |
Stabilised reinforced cellulose
|
| What you receive |
4 capsules, 1 operating instruction
|
| Ligand |
Primary amine (PA)
|
| Ligand density |
18 – 22 μeq/cm²
|
| Typical dynamic binding capacity 10% per unit |
3,5 g
|
| Maximum Pressure |
0,5 MPa
|
| pH stability |
2 - 14 (short term)
|
| Void volume |
320 ml
|
| Dimensions |
7,7 x 19,7 cm
|
| Reference protein |
Bovine serum albumin
|
| Membrane type |
Salt tolerant interaction membrane (STIC®)
|
Application Note
Brochure
-
Broch_Sartobind_SingleSep_SL-1521-e.pdf (1.270 KB)
Datasheet
-
Data_Sartobind_STIC-PA_SL-2065-e.pdf (675 KB)