Sartoclear^® P Module 293S5-P12-1DO--V

Proven technology with low investment costs

Scaleable from small the lab to production

Maximised throughput by optimized filter media

Safe & easy handling

Description

Sartoclear® P Depth filter Modules are especially designed to serve medium scale and large scale volumes from 100 litre and more in cell harvest and clarification applications. Sartoclear^® P Depth Filter Modules are available in 12” (1,8 m²) and 16” (3,6 m²) diameter and come with double O-ring (DO) or flat gasket (FA) adapter for the 6 different filtration grades. The cellulose structure forms a 3-dimensional matrix which serves high dirt holding capacities to collect Cells and Cell debris. The added filters aids like diatomaceous earth and resin binder additionally bind contaminants like host cell proteins, colloids and DNA. The use of small scale Sartoclear^® P Caps is recommended to screen for the most optimal filter grade per application. Sartoclear^® P depth filter products allow a gentle treatment of host cells and thus minimize the release of contaminants like proteolytic enzymes, lipoproteins, host cell proteins and DNA. Sartoclear® P products are also used for applications like growth medium purification, separation of cryo-precipitants and the removal of particles and lipids from serum and plasma applications.

Grade	Nominal retention (µm)	Thickness (mm)	Weight (kg/m²)	Ash content (%)	Flow rate (L/m²/min.)
C4	8	4,1	0,93	20	1250
C8H	4	4,1	1,08	35	700
F4H	1,5	4,1	1,26	45	205
F7H	1,0	4,0	1,42	50	100
S5	0,3	4,0	1,55	50	70
S9	0,1	4,0	1,64	48	42

Validation

Sartoclear^® Depth filter products are validated according to the USP Quality standards for WFI. Detailed information on test methods and specifications can be found in the corresponding validation guide.

Biosafety

All materials of this filter element meet the requirements of USP 26 Biological Reactivity tests <88> for plastics Class VI, (Systemic Injection, Intracutaneous and Implantation tests).

Metal extractables

See corresponding validation guide.

Product properties

Depth filter material	S5P
Retention Rate (s)	0,3 µm
Application	Bioburden reduction
Type	Depth filter module
Diameter	286 mm
Cartridge Height	304 mm
Pack size	2
Grade	S5-P

Technical attributes

Filter Material	Cellulosic depth filter media with inorganic filter aids
Support Layers	Polypropylene (PP)
Structural Compounds	Polypropylene (PP)
O-ring	EPDM
Bacterial Endotoxins	< 0,25 EU/ml
Extractables	Depth filter media meets or exceeds the Quality standards set for "Sterile Water for Injection" by USP 26.
Sterilisation	1 cycle of wet autoclaving 121°C at 1 bar (14.59 psi) for 30 min or 1 cycle in-line steam sterilization at 121°C for 60 min
Max. Differential Pressure	20 °C: 2 bar; 80 °C: 1 bar; 121 °C: 0,2 bar
Adapter	DO - Adapter
Diameter	30,5 cm
Filtration area	1,8 m²