BIOSTAT® A - Your professional start in cell cultivation and microbial fermentation

BIOSTAT® A is an entry-level bioreactor | fermenter designed for easy control of cell growth and fermentation. It is therefore ideal for educational purposes.

Simple and Automatic Aeration Control

The new aeration system of the BIOSTAT® A provides continuous automatic flow control over the full range of each gas used...

Simple and Automatic Aeration Control

The new aeration system of the BIOSTAT® A provides continuous automatic flow control over the full range of each gas used.
As a result, BIOSTAT® A does not require any manual adjustment of flow meters and therefore eliminates problems with pulsed aeration. Setting up the bioreactor for use is straightforward:
Just connect the aeration tubing, configure the aeration profile, enter the DO setpoint – that’s it!

For cell culture applications, interfaces for four gases (air, O2, CO2 and N2) are available for DO and pH control. The microbial version features two gas lines (air and O2) for DO control.

Integrated Chiller for Microbial Fermentation

Allows fermentation in any laboratory and minimizes water usage

You won’t need to worry about finding a suitable cooling water source for your bioreactor...

Integrated Chiller for Microbial Fermentation

Allows fermentation in any laboratory and minimizes water usage

You won’t need to worry about finding a suitable cooling water source for your bioreactor. Each BIOSTAT® A for microbial fermentation is equipped with a chiller that effectively removes heat from your culture. This reduces your cooling water usage, and you will not require a water supply line for cooling installed in your lab.
The only utility connections you need are electricity and gas supply to operate the BIOSTAT® A.

Intuitive Operation Even Outside a Laboratory

Thanks to the intuitive user interface, operating the BIOSTAT® A is ideal for beginners, reduces operating errors and speeds up training...

Intuitive Operation Even Outside a Laboratory

Thanks to the intuitive user interface, operating the BIOSTAT® A is ideal for beginners, reduces operating errors and speeds up training. Operation using a tablet or smartphone is a mode offered in the Advanced package and enables you to monitor and control the BIOSTAT® A on the move – in the laboratory, in the office or even at home.

Easy status checks for your pH and DO probes

BIOSTAT® A is equipped with digital pH and DO probes. These help you immediately recognize whether you can use a probe for the next cultivation batch...

Easy status checks for your pH and DO probes

BIOSTAT® A is equipped with digital pH and DO probes. These help you immediately recognize whether you can use a probe for the next cultivation batch. Moreover, the moisture-resistant plug connector ensures secure data transmission to the BIOSTAT® A at all times.

It’s the little things that make your life easier ...
... and enable you to take the next step.

Easy Load peristaltic pumps

Convenient data storage and analysis

Flexibility made easy

Higher cell densities with fed-batch processes

Install tubing in three seconds: Open, insert tubing, close – done! No more pinched fingers, torn gloves or tubing slippage in the peristaltic pump head.

Save your process data directly on the BIOSTAT® A; then easily transfer this data to your PC or laptop spreadsheet application for convenient analysis.

Select the type and size of your culture vessel on the BIOSTAT® A menu, and all settings including PID parameters will be automatically adjusted.

The Advanced package version of the BIOSTAT® A with fedbatch control lets you achieve higher cell densities than with standard batch control. Easily implement substrate profiles in the menu to control an external variable-speed pump.

Glass and Single-use
for More Flexibility – Every Day

The BIOSTAT® A is available with single-wall glass vessels in a choice of working volumes of 1, 2 or 5 liters maximum. Whether you select our reusable UniVessel® Glass version or our disposable UniVessel® SU unit with a maximum 2-liter working volume, you can use the same system controller.

Both the UniVessel® Glass and the UniVessel® SU feature the classic stirred-tank design to give you comparable results. The advantage: The same motor drives the stirrer of both vessels so you can easily change over from reusable to single-use or vice versa.

UniVessel® Glass

  • Classic stirred-tank design for easy scaling to larger volumes with all characterization data available up to 2,000 L
  • Proven sterile design and robustness
  • Also fits in small autoclaves, saving you additional investment costs

UniVessel® SU

  • Easy handling as the culture vessel is fully pre-assembled and sterilized: no parts to mount, no cleaning – just connect to get started
  • No room for an autoclave to sterilize your culture vessel? No problem! The UniVessel® SU is single-use, from the vessel to the sensors
  • Eliminates preliminary setup and post-cleaning procedures so you can better meet your tight experimental deadlines and utilize your time for more important tasks

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Multi-parallel Cultivation
for Faster Results ...

Perform screening studies efficiently with multi-parallel
cultivation. Screen your process variables and define
the conditions for optimal cell growth and enhanced
protein expression.

Download your trial data from the BIOSTAT® A to
your notebook, tablet or smartphone. For fast and
accurate analysis of your data, use our Chemometrics
Toolbox installed on your notebook or PC.

... Powered by BioPAT® MODDE and BioPAT® SIMCA

Quick results with little effort

Our Chemometrics Toolbox assists you in efficiently optimizing key process parameters, such as titer or cell density, so you will obtain meaningful results faster from your experiments.

DoE - BioPAT® MODDE

Thanks to its intuitive user guidance, this leading DoE software is the ideal tool for beginners in experimental design planning and performing trial runs, as well as analyzing and optimizing media and parameters for cultivation.
By performing only a few experiments, you can quickly and easily determine the relationship between process parameters and the relevant target figures, such as titer and product quality.

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MVDA - BioPAT® SIMCA

With BioPAT® SIMCA, you can quickly and easily compare the historical data of different cultivation batches to identify trends, correlations and dependencies.
The graphical user interface enables you to select the software functions intuitively. In addition, the Analysis Advisor guides you through the whole analysis process and generates easy-to-interpret graphs.

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